Immune dysfunction and the pathogenesis of AIDS-associated non-Hodgkin's lymphoma.
نویسندگان
چکیده
Much has been learned about how HIV-induced immune dysfunction contributes to B cell hyperactivation, and potentially, to the pathogenesis of AIDS-lymphoma. However, further studies are needed to fully understand how HIV infection and immune dysfunction promote B cell hyperactivation and the development/growth of AIDS-lymphoma. In particular, studies are needed to define the role of HHV8 vIL6, IL6 receptor-expression, and lymphocyte surface stimulatory molecules, in promoting B cell hyperactivation or lymphoma cell growth.
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ورودعنوان ژورنال:
- Memorias do Instituto Oswaldo Cruz
دوره 93 3 شماره
صفحات -
تاریخ انتشار 1998